Research

Adolescence typically marks a major transition to independence. Independence brings with it the need to make important decisions, such as where to forage, where to sleep, and when and where to reproduce. It also often requires a period of exploration with high tolerance for risk that is eventually followed by formation of more stable adult habits. In humans, adolescence also marks a critical moment for the development of addiction.

Anatomical studies have shown that the mammalian brain undergoes radical changes during adolescence, particularly in the frontal lobe, which integrates sensory and memory systems and coordinates flexible decision-making. We are focused on understanding the adolescent transition at the synaptic, circuit, and behavioral level. In particular, we want to understand:

How adolescent experience with drugs of abuse and natural reinforcers, such as food, alters neural circuitry and decision-making over the lifespan, and how neural plasticity can be harnessed to reverse addiction.

Approaches

Recent Publications

Faculty Forum: Characterizing Effects of Inequality on Brain Development & Strengthening Resilience against Adversity

October 2nd, 2016|Comments Off on Faculty Forum: Characterizing Effects of Inequality on Brain Development & Strengthening Resilience against Adversity

UC Berkeley's Vice Chancellor for Research is holding a faculty forum on Characterizing Effects of Inequality on Brain Development & Strengthening Resilience against Adversity on Tuesday, October 4th at the Faculty Club.  The event is convened by Linda Wilbrecht, Silvia Bunge, Daniela Kaufer, Julianna Deardorff, and Lance Kriegsfeld
.

Wilbrecht in Conversation with Tom Stoppard and Carey Perloff

October 1st, 2016|Comments Off on Wilbrecht in Conversation with Tom Stoppard and Carey Perloff

On Monday, October 3rd, Linda Wilbrecht will join Tom Stoppard and Carey Perloff in conversation at the ACT Theater. Tom Stoppard and Carey Perloff—In Conversation Monday, October 3, 7 p.m. A.C.T.'s Geary Theater Tony, Academy, and Olivier Award winner Tom Stoppard will join A.C.T. Artistic Director Carey Perloff “In Conversation” at The Geary Theater where they will discuss their decades-long collaboration and why Stoppard has long referred to A.C.T. as his “American home.” They will be joined on stage by neuroscientist Linda Wilbrecht from the University of California, Berkeley.

Lab News

Faculty Forum: Characterizing Effects of Inequality on Brain Development & Strengthening Resilience against Adversity

October 2nd, 2016|Comments Off on Faculty Forum: Characterizing Effects of Inequality on Brain Development & Strengthening Resilience against Adversity

UC Berkeley's Vice Chancellor for Research is holding a faculty forum on Characterizing Effects of Inequality on Brain Development & Strengthening

Wilbrecht in Conversation with Tom Stoppard and Carey Perloff

October 1st, 2016|Comments Off on Wilbrecht in Conversation with Tom Stoppard and Carey Perloff

On Monday, October 3rd, Linda Wilbrecht will join Tom Stoppard and Carey Perloff in conversation at the ACT Theater. Tom

Lung-Hao Tai’s collaborative work with Bo Li lab recently published

September 24th, 2016|Comments Off on Lung-Hao Tai’s collaborative work with Bo Li lab recently published

Lung-Hao Tai's collaborative work with the Bo Li lab was recently published as: Marcus Stephenson-Jones, Kai Yu, Sandra Ahrens, Jason